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Apr 23, 2018
Category: General
Posted by: admin

The Department of Microbiology is in the process of revising the syllabus of M.Sc. Microbiology program under Choice Based Credit System. The draft of the revised syllabus has been prepared after taking into consideration the feedback obtained from multiple stakeholders including the present students, the alumni, as well as prospective employers from the corporate sector. The Department invites your views and suggestions on the same which may be submitted only by email at latest by 5 PM on Friday, the 4th of May 2018. The draft of syllabus may be downloaded here.

Apr 17, 2018
Category: General
Posted by: admin

On 20-April-2018, Ms.Nivedita Gaur will present her pre-PhD submission seminar entitled -“The role of human tumor associated herpesvirus latent antigens in epithelial to mesenchymal transition of cancer cells" at 11AM in Seminar room of the Department. 

Apr 13, 2018
Category: General
Posted by: admin

On 13-Apr-2018, Ms.Ashima Dua will be presenting a paper which may be downloaded by clicking on the image below. This will be followed by work presentation by Mr.Gaurav Kumar.

Paper Cover

CMS - 2.2.7 - Skookumchuck


Dr.Swati Saha

Lab Members






2008 0NWARDS:

Chandra, U, Yadav, A, Kumar, D, & Saha, S. (2017).  Cell cycle stage-specific transcriptional activation of cyclins mediated by HAT2-dependent H4K10 acetylation of promoters in Leishmania donovani. PLoS Pathogens 13(9): e1006615

Yadav, A, Chandra, U, & Saha, S. (2016).  Histone acetyltransferase HAT4 modulates navigation across G2/M and re-entry into G1 in Leishmania donovani. Scientific Reports 6: 27510

Goswami, K, Arora, J, & Saha, S. (2015). Characterization of the MCM homohexamer from the thermoacidophilic euryarchaeon Picrophilus torridus. Sci. Rep.  5: 9057.

Kumar, D, & Saha, S. (2015). HAT3-mediated acetylation of PCNA precedes PCNA monoubiquitination following exposure to UV radiation in Leishmania donovani. Nucleic Acids Res. 43(11):5423-41

Arora, J, Goswami, K, & Saha, S. (2013). Characterization of the replication initiator Orc1/Cdc6 from the archaeon Picrophilus torridus. J Bacteriol. 196: 276-286.

Kumar, D, Kumar D & Saha, S. (2012).  A highly basic monopartite sequence at the N-terminal region is essential for targeting the DNA replication protein ORC1 to the nucleus in Leishmania donovani. Microbiology. 158: 1775-1782.

Kumar, D, Minocha, M, Rajanala, K. & Saha, S. (2012). The histone H4 lysine 14 acetylation in Leishmania donovani is mediated by the MYST family protein HAT4. Microbiology. 158: 328-337.

Minocha, N, Kumar, D, Rajanala, K, & Saha, S. (2011). Characterization of Leishmania donovani MCM4: expression patterns and interaction with PCNA. PLoS One 6 (7): e23107.

Minocha, N, Kumar, D, Rajanala, K, & Saha, S. (2011). Kinetoplast morphology and segregation pattern as a marker for cell cycle progression in Leishmania donovani. J. Euk. Microbiol. 58 (3): 249-253.

Kumar, D, Minocha, M, Rajanala, K. & Saha, S. (2009). The distribution pattern of proliferating cell nuclear antigen in the nuclei of Leishmania donovani. Microbiology 155: 3748-3757.

Kumar, S, Mukherji, A, & Saha, S. (2008). Expression and subcellular localization of ORC1 in Leishmania major. Biochem. Biophys. Res. Comm. 375: 74-79.



Saha, S, Shan Y, Mesner LD, Hamlin JL. (2004). The promoter of the Chinese hamster ovary dihydrofolate reductase gene regulates the activity of the local origin and helps define its boundaries. Genes Dev. 18: 397-410.

Saha, S,  Nicholson, A & Kapler, G.M. (2001).  Cloning and biochemical analysis of  the Tetrahymena origin binding protein TIF1.  Competitive DNA binding in vitro and in vivo to critical rDNA replication determinants. J. Biol. Chem. 276: 45417-45426.

Rao, D. N., Saha, S. & Krishnamurthy, V. (2000). ATP-dependent Restriction Enzymes. Progress in Nucleic Acid Research and Molecular Biology. 64: 1-63.

Mohammad, M., Saha, S. & Kapler, G. M.(2000). Three different proteins recognize a multifunctional determinant that controls replication initiation, fork arrest and transcription in Tetrahymena. Nucleic Acids Res. 28: 843-851.

Saha, S. & Kapler, G. M. (2000). Allele-specific protein-DNA interactions between the single stranded DNA-binding protein, ssA-TIBF, and DNA replication determinants in TetrahymenaJ. Mol. Biol. 295: 423-439.

Saha, S., Ahmad, I., Reddy, Y. V., Krishnamurthy, V. & Rao D. N. (1998). Functional analysis of conserved motifs in type III restriction-modification enzymes. Biol. Chem. 379: 511-517.

Saha, S. & Rao, D. N. (1997).  Mutations in the Res subunit of EcoPI restriction enzyme that affect ATP-dependent reactions. J. Mol. Biol. 269: 342-354.

Saha, S. & Rao, D. N. (1995).  ATP hydrolysis is required for DNA cleavage by EcoPI restriction enzyme. J. Mol. Biol. 247: 559-567.


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