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Apr 13, 2018
Category: General
Posted by: admin

On 13-Apr-2018, Ms.Ashima Dua will be presenting a paper which may be downloaded by clicking on the image below. This will be followed by work presentation by Mr.Gaurav Kumar.

Paper Cover

Apr 12, 2018
Category: General
Posted by: admin

12-Apr-2018: Notice for inviting applications for inclusion of name in panel for ad-hoc appointment of Assistant Professors in Microbiology Department in different colleges of University of Delhi. Last date of application is 07-May-2018. Notice, Proforma. Further details here.

CMS - 2.2.7 - Skookumchuck


Dr.Y.P. Khasa

Lab Members







Dagar VK, Adivitiya, & Khasa YP (2018). Combined effect of gene dosage and process optimization strategies on high-level production of recombinant human Interleukin-3 (hIL-3) in Pichia pastoris fed-batch culture. International Journal of Biological Macromolecules, 108: 999-1009

Dagar VK, Adivitiya, & Khasa YP (2017). High-level expression and efficient refolding of therapeutically important recombinant human Interleukin-3 (hIL-3) in E. coli. Protein Expression and Purification, 131:51-59.

Nash SD, Prevots RD, Kabyemela E, Khasa YP, Lee KL, Fried M, & Duffy PE (2017). A Malaria-Resistant Phenotype with Immunological Correlates in a Tanzanian Birth Cohort Exposed to Intense Malaria Transmission. American Journal of Tropical Medicine and Hygiene, 96:1190-1196

Singha TK, Gulati P, Mohanty A, Khasa YP, Kapoor RK & Kumar S (2017). Efficient genetic approaches for improvement of plasmid based expression of recombinant protein in Escherichia coli: A review. Process Biochemistry 55:17–31

Adivitiya, & Khasa YP (2017). The evolution of recombinant thrombolytics: Current status and future directions. Bioengineered, 8: 331-358.

Devi N, Adivitiya, & Khasa YP (2016). A combinatorial approach of N-terminus blocking and codon optimization strategies to enhance the soluble expression of recombinant hIL-7 in E. coli fed-batch culture Applied Microbiology and  Biotechnology, 100: 9979-9994

Dagar VK, Adivitiya, Devi N & Khasa YP (2016). Bioprocess development for extracellular production of recombinant human interleukin-3 (hIL-3) in Pichia pastoris. Journal of Industrial Microbiology and Biotechnology, 43:1373-1386.

Adivitiya, Dagar VK, Devi N & Khasa YP (2016). High level production of active streptokinase in Pichia pastoris fed-batch culture. International Journal of Biological Macromolecules. 83: 50–60

Khasa YP, Khushoo A & Mukherjee KJ (2013). Enhancing toxic protein expression in E. coli Fed batch culture using kinetic parameters: hGM-CSF as a model system. Journal of Bioscience and Bioengineering, 115: 291–297.

Kumar M  Kaur N, Gautam k, Pathak RK, Khasa YP,  Gupta LR (2013). Reporting Heavy Metal Resistance Bacterial Strains from Industrially Polluted Sites of Northern India Using Fatty Acid Methyl Ester (FAME) Analysis and Plasma-Atomic Emission Spectroscopy (ICP-AES). Advanced Science Letters, 19: 3311-3314

Shrivastava B, Nandal P, Sharma A, Jain KK, Khasa YP, Das TK, Mani V, Kewalramani NJ, Kundu SS  & Kuhad RC (2012).  Solid state bioconversion of wheat straw into digestible and nutritive ruminant feed by Ganoderma sp. rckk02. Bioresource Technology, 107: 347-351.

Kumar A, Gupta R, Shrivastava B, Khasa YP & Kuhad RC (2012). Xylanase production from an alkalophilic actinomycete isolate Streptomyces sp. RCK-2010, its characterization and application in saccharification of second generation biomass. Journal of Molecular Catalysis B: Enzymatic 74:170-177.

Khasa YP, Khushoo A, Tapryal S, Mukherjee KJ (2011). Optimization of human Granulocyte Macrophage-colony stimulating factor (hGM-CSF) expression using native asparaginase and xylanase gene’s signal sequences in Escherichia coli. Appl Biochem Biotechnol. 165:523-37.

Meagher MM, Seravalli JG, S. Swanson T, Ladd RG, Khasa YP, Inan M, Harner JC, Johnson SK, Cott KV, Lindsey C, Wannemacher R, & Smith LA. (2011) Process Development and cGMP Manufacturing of a Recombinant Ricin Vaccine: an Effective and Stable Recombinant Ricin A-Chain Vaccine RVEc™  Biotechnology Progress.  27:1036-1047

Deswal D, Khasa YP & Kuhad RC (2011) Optimization of Cellulase production by a brown rot fungus Fomitopsis sp. RCK2010 under Solid State Fermentation. Bioresource Technology, 102: 6065–6072

Khasa YP, Conrad S, Sengul M, Plautz S, Meagher MM & Inan M (2011). Isolation of Pichia pastoris PIR-gene family and their utilization for cell surface display and recombinant protein secretion. Yeast  28: 213–226.

Kuhad RC, Gupta R, Khasa YP, Singh A & Percival Zhang YH (2011). Bioconversion of pentose sugars to ethanol: present and future prospects. Renewable & Sustainable Energy Reviews 15: 4950– 4962

Gupta R, Khasa YP & Kuhad RC (2011). Evaluation of pre-treatment methods in improving the enzymatic saccharification of Cellulosic materials. Carbohydrate Polymers,  84:1103–1109.

Shrivastava B, Thakur S, Khasa YP, Gupte A, Puniya AK, & Kuhad RC (2011). White rot fungal conversion of wheat straw to energy rich cattle feed. Biodegradation 22: 823-31.

Gupta R, Mehta G, Khasa YP, & Kuhad RC (2010). Fungal delignification of lignocellulosic biomass improves the saccharification of cellulosics. Biodegradation, 22:797-804.

Tapryal S, Khasa YP & Mukherjee KJ (2010). Single chain Fv fragment specific for human GM-CSF: Selection and expression using a bacterial expression library. Biotechnology Journal, 1078-1089.

Kuhad RC, Gupta R, Khasa YP & Singh A (2010). Bioethanol production from Lantana camara (Red sage): Pretreatment, Saccharification and Fermentation. Bioresource Technology, 101:8348-8354.



Khasa YP, Khushoo A, Srivastava L & Mukherjee KJ (2007). Kinetic studies of constitutive hGM-CSF expression in continuous culture of Pichia Pastoris. Biotechnology Letters, 29: 1903-1908.

Pal Y, Khushoo A & Mukherjee KJ (2006). Process optimization of constitutive human granulocyte macrophage colony stimulating factor (hGM-CSF) expression in Pichia pastoris fed batch culture. Applied Microbiology and Biotechnology 69: 650-657.

Khushoo A, Pal Y & Mukherjee KJ (2005). Optimization of extracellular production of recombinant asparaginase in Escherichia coli in shake-flask and bioreactor. Applied Microbiology and Biotechnology 68: 189-197.

Khushoo A, Pal Y, Singh BN, & Mukherjee KJ (2004). Extracellular expression and single step purification of recombinant Escherichia coli L-asparaginase II. Protein Expression and Purification 38: 29-36.

Pal Y, Gupta JC and Mukherjee KJ. “Optimizing recombinant protein expression in the T7 system under the control of the proUp promoter”. Biotechnology Letters, 23: 41-46.



Babbal, Adivitiya, Mohanty S & Khasa YP (2018) Enzymes as therapeutic agents in: A handbook on high value fermentation products, Scrivener Publishing, edited by: Saurabh Saran, Vikash Babu, Asha Chaubey. In press.

Babbal, Adivitiya & Khasa YP (2017). Microbes as biocontrol agents  in: Probiotics and Plant Health, Springer,  edited by: Vivek Kumar, Manoj Kumar, Shivesh Sharma, Ram Prasad. Pgs 507-552.

Adivitiya, Dagar VK, &  Khasa YP (2017) Yeast expression systems: Current status and future prospects in  Yeast Diversity in Human Welfare, Springer, edited by: Tulasi Satyanarayana & Gotthard Kunze. Pgs 215-250.

Kumar S, Dagar VK, Khasa YP & Kuhad RC (2013) Genetically Modified Microorganisms (GMOs) for Bioremediation in: Biotechnology for Environmental Management and Resource Recovery, Springer, Pgs 191-218.

Kuhad RC, Gupta R & Khasa YP (2012) Microbial decolorization of colored industrial effluents in: Microbes in Environmental Management and Biotechnology, Springer, edited by: Satayanarayana T & Johri BN. Pgs. 787-813

Kuhad RC, Gupta R & Khasa YP (2011) Bioethanol production from lignocellulosics: an overview in: Wealth from waste edited by Banwari Lal Teri. Pgs 53-106. 

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