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May 27, 2018
Category: General
Posted by: admin

A report on Nipah virus outbreak ongoing in Kerela, written by Vishal Dashora (M.Sc. Final). 

May 19, 2018
Category: General
Posted by: admin

The online registration for admission to M.Sc. and Ph.D. Microbiology for academic year 2018-19 has started. The admission portals will remain open for registration till 07-Jun-2018. For registration, please visit P.G. admission portal of University here, and Ph.D. admission portal here.

May 7, 2018
Category: General
Posted by: admin

On 18-May-2018, Ms.Babbal will be presenting a paper titled 'DNA nanorobot functions as a cancer therapeutic...' which may be downloaded by clicking on the image below. This will be followed by work presentation by Ms. Meenu Saini.

May JC Cover

CMS - 2.2.7 - Skookumchuck
 

Publications

Dr.Rani Gupta

Lab Members

Publications

Projects

Sequence Submissions

Alumni

Gallery

​From 2012-2017:

2017:

Bindal, S., & Gupta, R. (2017). Hyperproduction of gamma-glutamyl transpeptidase from Bacillus licheniformis ER15 in the presence of high salt concentration. Preparative Biochemistry and Biotechnology, 47(2), 163-172.

Bindal, S., Sharma, S., Singh, T. P., & Gupta, R. (2017). Evolving transpeptidase and hydrolytic variants of gamma-glutamyl transpeptidase from Bacillus licheniformis by targeted mutations of conserved residue Arg109 and their biotechnological relevance. J of Biotechnology, 249, 82-90.

Dua, A., & Gupta, R. (2017). Functional characterization of hormone sensitive-like lipase from Bacillus halodurans: synthesis and recovery of pNP-laurate with high yields. Extremophiles, 21(5), 871-889.

Syal P., Verma V V., & Gupta, R. (2017). Targeted mutations and MD simulations of a methanol-stable lipase YLIP9 from Yarrowia lipolytica MSR80 to develop a biodiesel enzyme. IntJ Biol Macromo, 104, 78-88.

 

2016:

Bindal S and Gupta, R. (2016). Thermo- and salt-tolerant chitosan cross-linked γ-glutamyl transpeptidase from Bacillus licheniformis ER15. IntJ Biol Macromol. 91, 544-553.

Saini, M, Bindal, S and Gupta, R. (2016). Heterologous expression of γ-glutamyl transpeptidase from Bacillus atrophaeus GS-16 and its application in the synthesis of γ-D-glutamyl-L-tryptophan, a known immunomodulatory peptide. Enzyme Microb. Technol, doi.org/10.1016/j.enzmictec.2017.01.003.

Singh Y, Gupta N, Verma VV, Goel M, and Gupta, R. (2016). Selective disruption of disulphide bonds lowered activation energy and improved catalytic efficiency in TALipB from Trichosporon asahii MSR54: MD simulations revealed flexible lid and extended substrate binding area in the mutant. Biochem Biophys Res Commun, 472, 223-30.

Syal, P. and Gupta, R. (2016). Heterologous expression of lipases YLIP4, YLIP5, YLIP7, YLIP13 and YLIP15 from Yarrowia lipolytica MSR80 in E. coli: Substrate specificity, kinetic comparison and enantioselectivity. Biotech Appl Biochem, doi:10.1002/bab.1542.

 

2015:

Arti, A, Baronian, K, Kunze, G, Gupta, R. (2015). Extracellular expression of YlLip11 with a native signal peptide from Yarrowia lipolytica MSR80 in three different yeast hosts, Protein Express Purif, 110:138-144.

Gupta, R, Kumari, A, Syal, P, Singh, Y (2015) Molecular and functional diversity of yeast and fungal lipases: Their role in biotechnology and cellular physiology. Prog Lipid Research, 57: 40-54.

Kumari, A, Gupta, R. (2015) Functional characterization of a novel aspartic acid rich lipase, TALipC, from Trichosporon asahii MSR54: solvent-dependent enantio inversion during esterification of 1-phenylethanol, Biotechnol Lett, 37(1):121-30.

Singh, Y, Gupta, R. (2015). Novel S-enantioselective lipase TALipB from Trichosporon asahii MSR54: Heterologous expression, characterization, conformational stability and homology modeling. Enzyme and Microb.l Technol., 83, 29–39

 

2014:

Bindal, S., Gupta, R. (2014). L-Theanine synthesis using γ-glutamyl transpeptidase from Bacillus licheniformis ER-15. J Agric Food Chem, 62 (37), 9151–9159.

Kumari, A., Gupta, R. (2014). Functional characterization of a novel aspartic acid rich lipase, TALipC, from Trichosporon asahii MSR54: solvent-dependent enantio inversion during esterification of 1-phenylethanol. Biotechnol Lett, doi 10.1007/s10529-014-1648-5

Kumari, A., Gupta, R. (2014). Functional characterisation of novel enantioselective lipase TALipA from Trichosporon asahii sequence comparison revealed new signature sequence AXSXG among yeast lipase. Appl Biochem Biotechnol, doi 10.1007/s12010-014-1268-5

Kumari, A., Gupta, R. (2014). Novel strategy of using methyl esters as slow release methanol source during lipase expression by mut+ Pichia pastoris X33. PLoS ONE 9(8): e104272. doi:10.1371/journal.pone.0104272

 

2013:

Gupta R, Sharma R and Beg Q (2013), Revisiting microbial keratinases: Next generation proteases for sustainable biotechnology, Crit Rev Biotechnol, 33(2) 216-228

Kumari, A., Gupta, R. (2013), Heterologous expression, purification and characterization of thermostable lip11 from Yarrowia lipolytica in Pichia pastoris X33, J Prot Proteomics, 4, 5-10.

Rajput, R, Gupta, R. (2013), Expression of Bacillus pumilus keratinase rK27 in Bacillus subtilis: enzyme application on developing renewable flocculants from bone meal, Ann Microbiol, DOI 10.1007/s13213-013-0770-2

Rajput, R, Gupta, R. (2013), Thermostable keratinase from Bacillus pumilus KS12: Production, chitin crosslinking and degradation of Sup35NM aggregates, Bioresource Technol, 133, 118-126.

Rajput R, Verma VV, Chaudhary V and Gupta R (2013), A hydrolytic γ-glutamyltranspeptidase from thermo-acidophilic archaeon Picrophilus torridus: binding pocket mutagenesis and transpeptidation, Extremophiles, 17, 29-41

Rajput R, Verma VV, Chaudhary V, Gupta R. (2013) A hydrolytic γ-glutamyl transpeptidase from thermo-acidophilic archaeon Picrophilus torridus: binding pocket mutagenesis and transpeptidation. Extremophiles, 17(1):29-41

Rajput R, Gupta R. (2013) Thermostable keratinase from Bacillus pumilus KS12: Production, chitin crosslinking and degradation of Sup35NM aggregates. Bioresour Technol., 133C:118-126.

Sharma R, Verma VV and Gupta R (2013), Functional characterization of an extracellular keratinolytic protease, Ker AP from Pseudomonas aeruginosa KS-1: A putative aminopeptidase with PA domain, J. Mol. Catal., 91, 8-16

 

2012:

Kumari A, Gupta R. (2012) Extracellular expression and characterization of thermostable lipases, LIP8, LIP14 and LIP18, from Yarrowia lipolytica. Biotechnol Lett., 34(9):1733-9.

Murty NA, Tiwary E, Sharma R, Nair N, Gupta R. (2012) γ-Glutamyl transpeptidase from Bacillus pumilus KS 12: decoupling autoprocessing from catalysis and molecular characterization of N-terminal region. Enzyme Microb Technol., 50(3):159-64

Rajput R, Tiwary E, Sharma R, Gupta R. (2012). Swapping of pro-sequences between keratinases of Bacillus licheniformis and Bacillus pumilus: altered substrate specificity and thermostability. Enzyme Microb Technol.,51(3):131-135.