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Jun 13, 2022
Category: General
Posted by: admin

Prof.Yogender Pal Khasa and Dr. Vijay Verma of the Department of Microbiology with DBT secretary Dr.Rajesh Gokhale

PMaidan

Jun 3, 2022
Category: General
Posted by: admin

An edit window has been activated to make corrections in the submitted PG registration forms for the registered candidates applying for Post-graduate programs at the University of Delhi from 10:00 a.m.,Tuesday, May 24, 2022 to 11:59 p.m., Friday June 10, 2022. A notice regarding the same was uploaded on the admission website of the University of Delhi here. Applicants are advised to avail this opportunity if required before deadline. 

Jun 2, 2022
Category: General
Posted by: admin

Quotations are invited through e-procurement portal for tender under two bid system for supply and installation of "One unit of Bacteriological Incubator-Shaker (Refrigerated Floor Model)". (Tender ID: 2022_DU_692235_1). The last date for bid submission is 25-June, 2022. The details may be downloaded here.

CMS - 2.2.7 - Skookumchuck
 

Publications

Prof.Rani Gupta

Lab Members

Publications

Projects

Sequence Submissions

Alumni

Gallery

​From 2012-2017:

2017:

Bindal, S., & Gupta, R. (2017). Hyperproduction of gamma-glutamyl transpeptidase from Bacillus licheniformis ER15 in the presence of high salt concentration. Preparative Biochemistry and Biotechnology, 47(2), 163-172.

Bindal, S., Sharma, S., Singh, T. P., & Gupta, R. (2017). Evolving transpeptidase and hydrolytic variants of gamma-glutamyl transpeptidase from Bacillus licheniformis by targeted mutations of conserved residue Arg109 and their biotechnological relevance. J of Biotechnology, 249, 82-90.

Dua, A., & Gupta, R. (2017). Functional characterization of hormone sensitive-like lipase from Bacillus halodurans: synthesis and recovery of pNP-laurate with high yields. Extremophiles, 21(5), 871-889.

Syal P., Verma V V., & Gupta, R. (2017). Targeted mutations and MD simulations of a methanol-stable lipase YLIP9 from Yarrowia lipolytica MSR80 to develop a biodiesel enzyme. IntJ Biol Macromo, 104, 78-88.

 

2016:

Bindal S and Gupta, R. (2016). Thermo- and salt-tolerant chitosan cross-linked γ-glutamyl transpeptidase from Bacillus licheniformis ER15. IntJ Biol Macromol. 91, 544-553.

Saini, M, Bindal, S and Gupta, R. (2016). Heterologous expression of γ-glutamyl transpeptidase from Bacillus atrophaeus GS-16 and its application in the synthesis of γ-D-glutamyl-L-tryptophan, a known immunomodulatory peptide. Enzyme Microb. Technol, doi.org/10.1016/j.enzmictec.2017.01.003.

Singh Y, Gupta N, Verma VV, Goel M, and Gupta, R. (2016). Selective disruption of disulphide bonds lowered activation energy and improved catalytic efficiency in TALipB from Trichosporon asahii MSR54: MD simulations revealed flexible lid and extended substrate binding area in the mutant. Biochem Biophys Res Commun, 472, 223-30.

Syal, P. and Gupta, R. (2016). Heterologous expression of lipases YLIP4, YLIP5, YLIP7, YLIP13 and YLIP15 from Yarrowia lipolytica MSR80 in E. coli: Substrate specificity, kinetic comparison and enantioselectivity. Biotech Appl Biochem, doi:10.1002/bab.1542.

 

2015:

Arti, A, Baronian, K, Kunze, G, Gupta, R. (2015). Extracellular expression of YlLip11 with a native signal peptide from Yarrowia lipolytica MSR80 in three different yeast hosts, Protein Express Purif, 110:138-144.

Gupta, R, Kumari, A, Syal, P, Singh, Y (2015) Molecular and functional diversity of yeast and fungal lipases: Their role in biotechnology and cellular physiology. Prog Lipid Research, 57: 40-54.

Kumari, A, Gupta, R. (2015) Functional characterization of a novel aspartic acid rich lipase, TALipC, from Trichosporon asahii MSR54: solvent-dependent enantio inversion during esterification of 1-phenylethanol, Biotechnol Lett, 37(1):121-30.

Singh, Y, Gupta, R. (2015). Novel S-enantioselective lipase TALipB from Trichosporon asahii MSR54: Heterologous expression, characterization, conformational stability and homology modeling. Enzyme and Microb.l Technol., 83, 29–39

 

2014:

Bindal, S., Gupta, R. (2014). L-Theanine synthesis using γ-glutamyl transpeptidase from Bacillus licheniformis ER-15. J Agric Food Chem, 62 (37), 9151–9159.

Kumari, A., Gupta, R. (2014). Functional characterization of a novel aspartic acid rich lipase, TALipC, from Trichosporon asahii MSR54: solvent-dependent enantio inversion during esterification of 1-phenylethanol. Biotechnol Lett, doi 10.1007/s10529-014-1648-5

Kumari, A., Gupta, R. (2014). Functional characterisation of novel enantioselective lipase TALipA from Trichosporon asahii sequence comparison revealed new signature sequence AXSXG among yeast lipase. Appl Biochem Biotechnol, doi 10.1007/s12010-014-1268-5

Kumari, A., Gupta, R. (2014). Novel strategy of using methyl esters as slow release methanol source during lipase expression by mut+ Pichia pastoris X33. PLoS ONE 9(8): e104272. doi:10.1371/journal.pone.0104272

 

2013:

Gupta R, Sharma R and Beg Q (2013), Revisiting microbial keratinases: Next generation proteases for sustainable biotechnology, Crit Rev Biotechnol, 33(2) 216-228

Kumari, A., Gupta, R. (2013), Heterologous expression, purification and characterization of thermostable lip11 from Yarrowia lipolytica in Pichia pastoris X33, J Prot Proteomics, 4, 5-10.

Rajput, R, Gupta, R. (2013), Expression of Bacillus pumilus keratinase rK27 in Bacillus subtilis: enzyme application on developing renewable flocculants from bone meal, Ann Microbiol, DOI 10.1007/s13213-013-0770-2

Rajput, R, Gupta, R. (2013), Thermostable keratinase from Bacillus pumilus KS12: Production, chitin crosslinking and degradation of Sup35NM aggregates, Bioresource Technol, 133, 118-126.

Rajput R, Verma VV, Chaudhary V and Gupta R (2013), A hydrolytic γ-glutamyltranspeptidase from thermo-acidophilic archaeon Picrophilus torridus: binding pocket mutagenesis and transpeptidation, Extremophiles, 17, 29-41

Rajput R, Verma VV, Chaudhary V, Gupta R. (2013) A hydrolytic γ-glutamyl transpeptidase from thermo-acidophilic archaeon Picrophilus torridus: binding pocket mutagenesis and transpeptidation. Extremophiles, 17(1):29-41

Rajput R, Gupta R. (2013) Thermostable keratinase from Bacillus pumilus KS12: Production, chitin crosslinking and degradation of Sup35NM aggregates. Bioresour Technol., 133C:118-126.

Sharma R, Verma VV and Gupta R (2013), Functional characterization of an extracellular keratinolytic protease, Ker AP from Pseudomonas aeruginosa KS-1: A putative aminopeptidase with PA domain, J. Mol. Catal., 91, 8-16

 

2012:

Kumari A, Gupta R. (2012) Extracellular expression and characterization of thermostable lipases, LIP8, LIP14 and LIP18, from Yarrowia lipolytica. Biotechnol Lett., 34(9):1733-9.

Murty NA, Tiwary E, Sharma R, Nair N, Gupta R. (2012) γ-Glutamyl transpeptidase from Bacillus pumilus KS 12: decoupling autoprocessing from catalysis and molecular characterization of N-terminal region. Enzyme Microb Technol., 50(3):159-64

Rajput R, Tiwary E, Sharma R, Gupta R. (2012). Swapping of pro-sequences between keratinases of Bacillus licheniformis and Bacillus pumilus: altered substrate specificity and thermostability. Enzyme Microb Technol.,51(3):131-135.