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Mar 14, 2019
Category: General
Posted by: admin

Bids are invited through eprocurement portal (Tender ID: 2019_DU_455178_1) for purchase of three safety cabinets for storing flammable and corrosive liquids such as acids and alcohols. Details may be downloaded here. Last date of submission is 20-March-2019.

Mar 13, 2019
Category: General
Posted by: admin

Applications are invited for temporary post of JRF and Lab attendant in a DBT funded project. Last date for application is 13-Apr-2019. The details regarding qualifications, emoluments and application process may be downloaded here.

Mar 8, 2019
Category: General
Posted by: admin

Title: "Screening for host factors and neutralizing mAbs for respiratory virus infections". Date and Time: March 11, 2019 (Monday) at 11AM. Venue: Seminar Room in Department of Microbiology (1st Floor of Bachhawat Block). This talk will be focused on using unbiased discovery approaches to identify human host factors required for hantavirus entry and neutralizing monoclonal antibodies (mAbs) against respiratory syncytial virus (RSV).

CMS - 2.2.7 - Skookumchuck
 

Publications

Dr.Swati Saha

Lab Members

Publications

Projects

Submissions

Alumni

Gallery

2008 0NWARDS:

Chandra, U, Yadav, A, Kumar, D, & Saha, S. (2017).  Cell cycle stage-specific transcriptional activation of cyclins mediated by HAT2-dependent H4K10 acetylation of promoters in Leishmania donovani. PLoS Pathogens 13(9): e1006615

Yadav, A, Chandra, U, & Saha, S. (2016).  Histone acetyltransferase HAT4 modulates navigation across G2/M and re-entry into G1 in Leishmania donovani. Scientific Reports 6: 27510

Goswami, K, Arora, J, & Saha, S. (2015). Characterization of the MCM homohexamer from the thermoacidophilic euryarchaeon Picrophilus torridus. Sci. Rep.  5: 9057.

Kumar, D, & Saha, S. (2015). HAT3-mediated acetylation of PCNA precedes PCNA monoubiquitination following exposure to UV radiation in Leishmania donovani. Nucleic Acids Res. 43(11):5423-41

Arora, J, Goswami, K, & Saha, S. (2013). Characterization of the replication initiator Orc1/Cdc6 from the archaeon Picrophilus torridus. J Bacteriol. 196: 276-286.

Kumar, D, Kumar D & Saha, S. (2012).  A highly basic monopartite sequence at the N-terminal region is essential for targeting the DNA replication protein ORC1 to the nucleus in Leishmania donovani. Microbiology. 158: 1775-1782.

Kumar, D, Minocha, M, Rajanala, K. & Saha, S. (2012). The histone H4 lysine 14 acetylation in Leishmania donovani is mediated by the MYST family protein HAT4. Microbiology. 158: 328-337.

Minocha, N, Kumar, D, Rajanala, K, & Saha, S. (2011). Characterization of Leishmania donovani MCM4: expression patterns and interaction with PCNA. PLoS One 6 (7): e23107.

Minocha, N, Kumar, D, Rajanala, K, & Saha, S. (2011). Kinetoplast morphology and segregation pattern as a marker for cell cycle progression in Leishmania donovani. J. Euk. Microbiol. 58 (3): 249-253.

Kumar, D, Minocha, M, Rajanala, K. & Saha, S. (2009). The distribution pattern of proliferating cell nuclear antigen in the nuclei of Leishmania donovani. Microbiology 155: 3748-3757.

Kumar, S, Mukherji, A, & Saha, S. (2008). Expression and subcellular localization of ORC1 in Leishmania major. Biochem. Biophys. Res. Comm. 375: 74-79.

 

1995-2004:

Saha, S, Shan Y, Mesner LD, Hamlin JL. (2004). The promoter of the Chinese hamster ovary dihydrofolate reductase gene regulates the activity of the local origin and helps define its boundaries. Genes Dev. 18: 397-410.

Saha, S,  Nicholson, A & Kapler, G.M. (2001).  Cloning and biochemical analysis of  the Tetrahymena origin binding protein TIF1.  Competitive DNA binding in vitro and in vivo to critical rDNA replication determinants. J. Biol. Chem. 276: 45417-45426.

Rao, D. N., Saha, S. & Krishnamurthy, V. (2000). ATP-dependent Restriction Enzymes. Progress in Nucleic Acid Research and Molecular Biology. 64: 1-63.

Mohammad, M., Saha, S. & Kapler, G. M.(2000). Three different proteins recognize a multifunctional determinant that controls replication initiation, fork arrest and transcription in Tetrahymena. Nucleic Acids Res. 28: 843-851.

Saha, S. & Kapler, G. M. (2000). Allele-specific protein-DNA interactions between the single stranded DNA-binding protein, ssA-TIBF, and DNA replication determinants in TetrahymenaJ. Mol. Biol. 295: 423-439.

Saha, S., Ahmad, I., Reddy, Y. V., Krishnamurthy, V. & Rao D. N. (1998). Functional analysis of conserved motifs in type III restriction-modification enzymes. Biol. Chem. 379: 511-517.

Saha, S. & Rao, D. N. (1997).  Mutations in the Res subunit of EcoPI restriction enzyme that affect ATP-dependent reactions. J. Mol. Biol. 269: 342-354.

Saha, S. & Rao, D. N. (1995).  ATP hydrolysis is required for DNA cleavage by EcoPI restriction enzyme. J. Mol. Biol. 247: 559-567.

 

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